You can remove a portal connection on the Portals page in the ArcGIS Pro Settings. From an open project, click the Project tab on the ribbon. Or, from the ArcGIS Pro start page, click Settings in the lower left corner. In the list on the left, click Portals. On the Portals page, in the list of portals, select the portal you want to remove and click Remove Remove. If you have a Named User license, you can’t remove your licensing portal (marked with a key icon). Learn more about managing portal connections.